Pracovní pozice

The Institute of Biotechnology of the Czech Academy of Sciences (IBT) announces an open competition in accordance with the Act No. 283/1992 Coll. on the Czech Academy of Sciences, and the Statutes of the Czech Academy of Sciences for the position:

Postdoc in the Laboratory of Tumor Resistance

TOPIC: CANCER RESISTANCE, MITOCHONDRIA, IRON METABOLISM

• Postdoctoral fellow will be responsible for data mining and evaluating the effects of potential target molecules associated with cancerogenesis, particularly those linked to tamoxifen and taxane resistance, mitochondrial function, and iron metabolism.
• The role involves both in vitro tissue culture work and in vivo animal handling and treatment.

We Offer:

• Dynamic Research Environment: Join a young, enthusiastic, and motivated team. Learn more about our work and team on our website: www.ibt.cas.cz
• Top Research Facilities: Work at the Institute of Biotechnology, Czech Academy of Sciences, located in the BIOCEV Research Centre, equipped with state-of-the-art service facilities.
• Competitive Package: Engage in an exciting research topic with a competitive salary, five weeks of vacations and benefits.

Requirements:

• Educational Background: PhD in Cellular Biology, Biochemistry, or Molecular Biology.
• Proven Research Experience: Demonstrated history of research activities and contributions to the field.
• Active Research Participation: Ability to engage actively in ongoing research projects.
• Communication & Teamwork: Excellent communication skills with a strong ability to work collaboratively in a team environment.
• Leadership Skills: Capable of mentoring and guiding PhD students, with strong leadership and interpersonal skills.
• Language Proficiency: Advanced level of written and spoken English.
• Relevant Expertise (Preferred): Experience with mitochondrial and cancer biology and CRISPR/NGS/sc RNA-seq methods is an advantage.

The contract is offered for one year with a possible extension.

Application deadline: September 30, 2024.

We look forward to welcoming you to our team!

• For more information, please, contact Jaroslav Truksa (jaroslav.truksa@ibt.cas.cz)
• Send written applications including cover letter, professional CV and recommendation letter in electronic form to hr@ibt.cas.cz
• More details on the processing of personal data are available on the website: https://www.ibt.cas.cz/cs/o-ustavu/oficialni-dokumenty/gdpr/.

Specialist, Software Engineering

• We are investing in ourselves to change the way our company develops and harnesses the power of Artificial Intelligence. If you are eager to spearhead groundbreaking technologies that will make a meaningful impact on people's lives within a world-renowned pharmaceutical company, then look no further, we have the perfect role for you!  
• The Software Engineer will redefine what is possible and unleash the potential of Artificial Intelligence in applications. Reporting to the Director of Engineering in HyperAutomation & AI within our Chief Technology Office, this position is responsible for designing, building, and integrating AI into production systems to ensure seamless operation for our company. The ideal candidate is a tenacious problem solver with the keen ability to move with urgency to create sustainable solutions.  
• Join our team as we pioneer innovative solutions that redefine the boundaries of pharmaceutical advancements on a global scale.

Key Responsibilities:

• Software development on backend and frontend (Python, SQL, REST, JavaScript, TypeScript / node.js + React framework)
• Write efficient and maintainable code following best practices in software engineering.
• Working with DevSecOps tools for deploying and versioning code.
• Deploy solutions on the cloud with CI/CD integration.
• Deliver enterprise AI projects, products, and platforms with a focus on scalability and reusability.
• Work on technical pilots and feasibility studies of new opportunities to create value and transitioning successful pilots to scalable production implementations.
• Develop integrations with other applications and services.
• Develop unit tests of the application both positive and negative cases.
• Application release and second level support
• Stay up to date with the latest advancements in software engineering technologies.
• Participate in Agile ceremonies with the team to execute on prioritized projects and features.
• Work closely with cross-functional teams, including product managers, data scientists, and software engineers, to understand requirements and deliver AI-driven solutions. 

Education:

• Candidates are evaluated case-by-case but appreciate qualifications in quantitative, scientific and technology disciplines such as Mathematics, Statistics, Computer Science, Data Science, Analytics, Physics, and Bioinformatics. 

Requirements:

• 2+ years hands-on coding and software design experience building robust and scalable software using Python, SQL, REST, JavaScript, TypeScript / node.js + React framework
• Experience in building data intensive applications in a modern technology stack: Cloud services (AWS, Azure), data pipelines, SQL/No-SQL databases (graph databases is a plus)
• Familiar with class design, class architecture, and maintaining applications
• Familiar building and consuming web-based APIs
• Familiar with CI/CD environments and test-driven development leveraging a Version Control system including different branching strategies
• Strong collaboration and communication skills for working with cross-functional teams.
• Familiar with developing unit testing and different testing strategies such as performance testing.
• Understanding of System Integration patterns. 

Preferred: 

• Experience working in an Agile Methodology
• Familiar in fields related to artificial intelligence, machine learning, and data science.
• Knowledge of Generative AI solutions and applications
• Experience working with AWS Cloud 
• Experience with building, deploying, and managing docker images. 

What we look for…

• Imagine getting up in the morning for a job as important as helping to save and improve lives around the world. Here, you have that opportunity. You can put your empathy, creativity, digital mastery, or scientific genius to work in collaboration with a diverse group of colleagues who pursue and bring hope to countless people who are battling some of the most challenging diseases of our time. Our team is constantly evolving, so if you are among the intellectually curious, join us — and start making your impact today.
• We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace. #aiml2024

Search Firm Representatives Please Read Carefully 

• Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Employee Status:

• Regular

Flexible Work Arrangements:

• Hybrid

Required Skills:

• Agile Methodology, Automated Testing, Cloud Based Services, DevOps, JavaScript, Software Development, Software Development Life Cycle (SDLC), System Designs, TypeScript

Preferred Skills:

• Artificial Intelligence (AI), Computer Science, C Sharp (Programming Language), Python (Programming Language), Software Design, Structured Query Language (SQL)

Requisition ID:

• R302741

Do you want to know more about our Gen AI team? Find more information here.

Are you interested in this position? Apply here.

Specialist, AI Engineering

• We are investing in ourselves to change the way our company develops and harnesses the power of Artificial Intelligence. If you're eager to spearhead groundbreaking technologies that will make a meaningful impact on people's lives within a world-renowned pharmaceutical company, then look no further, we have the perfect role for you! 
• The AI Engineer will redefine what’s possible and unleash the potential of Artificial Intelligence. Reporting to the Director of Engineering in Hyperautomation & AI within our Chief Technology Office, this position is responsible for integrating AI models into production systems to ensure seamless operation for our company. The ideal candidate is a tenacious problem solver with the keen ability to move with urgency to create sustainable solutions.   
• Join our team as we pioneer innovative solutions that redefine the boundaries of pharmaceutical advancements on a global scale.

Key Responsibilities:

• Write efficient and maintainable code following best practices in software engineering.
• Working with DevSecOps tools for deploying and versioning code.
• Conduct thorough research and analysis of retrieval techniques, language models, and generative AI methodologies.
• Collaborate with data engineers to ensure data pipeline efficiency and accuracy.
• Continuously iterate and refine retrieval augmented generation (RAG) methods and processes based on experimentation, analysis, and feedback.  This will include embedding, chunking, loading, and search algorithm setup.
• Experiment with different retrieval strategies, including information retrieval, nearest-neighbor searches, or knowledge graph-based retrievals, to augment generative AI models.
• Algorithm Optimization - Optimize and fine-tune AI models for performance, scalability, and accuracy.
• Work closely with cross-functional teams, including product managers, data scientists, and software engineers, to understand requirements and deliver AI-driven solutions.
• Present findings and insights to stakeholders and contribute to strategic decision-making.
• Document AI models, algorithms, and processes thoroughly.
• Prepare technical reports and presentations to communicate results and methodologies.
• Stay up to date with the latest advancements in AI and machine learning technologies.
• Participate in Agile ceremonies with the team to execute on prioritized projects and features.
• Implement automated testing and monitoring techniques to ensure the accuracy and reliability of AI systems. 

Education:

• Candidates are evaluated case-by-case but appreciate qualifications in quantitative, scientific and technology disciplines such as Mathematics, Statistics, Computer Science, Data Science, Analytics, Physics, and Bioinformatics. 

Requirements:

• 2+ years of experience in AI Engineering. 
• Strong programming skills in Python. 
• Familiar in building scalable AI Solutions within a modern technology stack which includes cloud services, data pipelines, database, and other necessary tooling. 
• Familiar with CI/CD and test-driven development 
• Experience in building Restful APIs for AI models. 
• Familiar with of machine learning concepts (i.e. neural networks, optimization algorithms, evaluation metrics). 
• Familiar with Retrieval Augmented Generation (RAG) techniques 
• Familiarity with prompt engineering techniques, such as instruction design, template-based approaches, rule-based conditioning, or fine-tuning strategies. 
• Strong communication and collaboration skills. 
• Must be analytical, detail-oriented, and able to manage multiple projects simultaneously.

Preferred:

• Experience working in an Agile Methodology. 
• Additional programing languages such as Node.js / TypeScript, C#, or Java 
• Demonstrated experience in developing and refining prompts for generative AI models, preferably in creative or text generation domains. 
• Experience with AWS Cloud. 
• Experience with building, deploying, and managing docker images.

What we look for…

• Imagine getting up in the morning for a job as important as helping to save and improve lives around the world. Here, you have that opportunity. You can put your empathy, creativity, digital mastery, or scientific genius to work in collaboration with a diverse group of colleagues who pursue and bring hope to countless people who are battling some of the most challenging diseases of our time. Our team is constantly evolving, so if you are among the intellectually curious, join us — and start making your impact today.
• We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace. #aiml2024

Search Firm Representatives Please Read Carefully

• Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Required Skills:

• AI Systems, Artificial Intelligence (AI), Machine Learning, Python (Programming Language), Software Development, Software Development Life Cycle (SDLC), Testing

Preferred Skills:

• AWS Cloud Computing, Computer Science

Do you want to know more about our Gen AI team? Find more information here.

Are you interested in this position? Apply here.