Pracovní pozice

PhD thesis in synthetic biology for the development of living therapeutic materials

• The INM Research Department Materials Synthetic Biology is looking for a Doctoral Researcher (F/M/D) with experience in biology, protein biochemistry, and/or microbiology.
• The project will focus on the development of safety-by-design strategies for applying living therapeutic materias.
• The PhD thesis will be embedded in the Leibniz Science Campus on Living Therapeutic Materials (https://www.lsclifemat.de), an interdisciplinary consortium aiming at the development of living drug delivery devices.
• Within this consortium, synthetic biologists, materials scientists, microbiologists, and clinicians are working together in interdisciplinary projects.
• The position is available immediately, a later starting point is also possible.

YOUR TASKS

• Perform molecular biology techniques, specifically molecular cloning techniques (e.g., Gibson assembly, restriction enzyme cloning).
• Bacterial production of engineered proteins in E. coli or other microorganisms.
• Protein purification and characterization via IMAC, SEC, SDS-PAGE, WB, etc.
• Analysis of bacterial longevity and viability using multiple detection techniques (FACS, microscope, spectrophotometer).
• Collaboration on the analysis of created bacteria in Zebrafish models.
• Analyse data, contribute to scientific publications, and present research findings.

YOUR PROFILE

• Master's degree in biochemistry, microbiology, biotechnology, or a related field.
• Strong experience with molecular cloning techniques.
• Proven experience with prokaryotic protein production, purification, and characterization.
• Familiarity with microbial culture and bioprocesses.
• Ability to work effectively as a member of an international, multi-disciplinary team.

WE OFFER

• An exciting opportunity to participate in the development of a unique Living Therapeutic Material (LTM).
• A collaborative environment with researchers experienced in protein-based hydrogel formation, protein engineering, and the development of engineered living materials.
• Opportunities for professional development and training to support highquality research and further enhance your profile.

IF YOU ARE INTERESTED, PLEASE SEND US FOLLOWING THROUGH THE APPLICATION SYSTEM

• Motivation letter
• CV
• Publication list (if available)
• Contact details of two references

We are looking forward to receiving your application by July 31st, 2025 via the application portal.

For more information on the Department of Materials Synthetic Biology, please see:

• Materials Synthetic Biology - INM
• If you have any questions or would require further information, please do not hesitate to contact Dr. Veronika Vetýšková (veronika.vetyskova@leibniz-inm.de) or Prof. Wilfried Weber (wilfried.weber@leibniz-inm.de).
• The INM practices an open and appreciative corporate culture in which the existing diversity is promoted and lived.
• The institute is an equal-opportunity employer with a certified family-friendly policy, and it provides offers for a better work life balance, flextime and mobile working.
• We promote the professional opportunities of women and strongly encourage them to apply. Severely disabled applicants with equal qualifications and aptitude will be given preferential consideration.